Fabulous winter lights in Luxembourg and (Post)modern thermodynamics—a school and workshop with a philosophical twist, in which I had the honor to give a short talk.
Frenesy-entropy decomposition in “action”
R. Belousov1, S. Savino1, 2, P. Moghe1, 3, T. Hiiragi1, 3, L. Rondoni2, A. Erzberger1.
1 EMBL—European Molecular Biology Laboratory, Meyerhofstraße 1, 69117 Heidelberg, Germany; 2 PoliTo—Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Turin, Italy; 3 Hubrecht institute, Uppsalalaan 8, 3584 CT Utrecht, Netherlands.
The concept of frenesy has not yet received as much attention in the natural sciences as the related concept of entropy, especially outside the field of stochastic thermodynamics. In my contribution, I will discuss how the frenetic part of a stochastic action—the time-symmetric counterpart of entropy—reflects the kinetic and transport properties of physical systems. In particular, using a cell sorting process in mouse embryogenesis as an example, I will show how the frenetic properties of a system are incorporated into a novel formulation of cellular Potts models, widely used in developmental biology. Applications of this formalism to other similar models described as discrete-state processes will also be covered.